TY - JOUR T1 - Preoperative Masseter Muscle Sarcopenia Predicts Mortality in Patients With Oesophageal Cancer JF - Anticancer Research JO - Anticancer Res SP - 301 LP - 310 DO - 10.21873/anticanres.15486 VL - 42 IS - 1 AU - TEPPEI KAMADA AU - HIRONORI OHDAIRA AU - EISAKU ITO AU - YOSHINOBU FUSE AU - JUNJI TAKAHASHI AU - KEIGO NAKASHIMA AU - YUICHI NAKASEKO AU - MASASHI YOSHIDA AU - KEN ETO AU - YUTAKA SUZUKI Y1 - 2022/01/01 UR - http://ar.iiarjournals.org/content/42/1/301.abstract N2 - Background/Aim: The impact of masseter muscle sarcopenia on the prognosis of patients with oesophageal cancer after oesophagectomy remains unclear. Patients and Methods: We retrospectively analysed data from 70 patients with oesophageal cancer who underwent oesophagectomy between 2013 and 2019. Overall survival and disease-free survival rates were analysed using Cox proportional hazards models and Kaplan–Meier curves with the log-rank test. Results: Masseter muscle sarcopenia was diagnosed in 36 patients. Multivariate analysis identified cytokeratin 19 fragment >1.1 (p=0.04); stage II, III, and IV cancer (p=0.01); and masseter muscle sarcopenia (p<0.01) as significant independent predictors of disease-free survival. Stage II, III, and IV cancer (p<0.01); masseter muscle sarcopenia (p<0.01); and postoperative pneumonia (p<0.01) were significant independent predictors of overall survival. Conclusion: Preoperative masseter muscle sarcopenia could be a strong predictor of long-term outcomes in patients who undergo oesophagectomy for oesophageal cancer. ER -