RT Journal Article
SR Electronic
T1 Pancreatectomy With Artery <em>En-bloc</em> Resection for Pancreatic Neck/Body Cancer: A Single-arm Pilot Study
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 217
OP 227
DO 10.21873/anticanres.15476
VO 42
IS 1
A1 KEN-ICHI OKADA
A1 MANABU KAWAI
A1 SEIKO HIRONO
A1 SHINYA HAYAMI
A1 MOTOKI MIYAZAWA
A1 YUJI KITAHATA
A1 MASAKI UENO
A1 RYOHEI KOBAYASHI
A1 ATSUSHI MIYAMOTO
A1 YOSHITAKA WADA
A1 SHINICHI ASAMURA
A1 HIROKI YAMAUE
YR 2022
UL http://ar.iiarjournals.org/content/42/1/217.abstract
AB Background/Aim: The potential benefits of pancreatectomy with major arterial resection have been studied in the past, but findings remain controversial. Pancreatic neck/body cancer (PNBC) involving arteries frequently requires combined resection of the pancreas, artery and portal vein. Patients and Methods: Nine prospectively-registered consecutive patients with PNBC were enrolled, all underwent pancreatoduodenectomy with common hepatic artery en-bloc resection (PD-CHAR). We investigated the safety of PD-CHAR by blood flow evaluation with intraoperative indocyanine green fluorescence imaging in reconstructed vessels/organs. Results: Among patients who underwent PD-CHAR, there was no severe morbidity. Artery/portal vein combined resection and reconstruction was performed in all patients. Four (44%) patients had pathological positivity for cancer cell invasion into the nerve plexus of artery at the site of radiographic artery involvement, although one (11%) was diagnosed with pathological artery involvement. Conclusion: PD-CHAR following neoadjuvant therapy might be feasible for PNBC without severe postoperative complications. Survival benefits in PNBC should be confirmed in further studies.