PT  - JOURNAL ARTICLE
AU  - KEN-ICHI OKADA
AU  - MANABU KAWAI
AU  - SEIKO HIRONO
AU  - SHINYA HAYAMI
AU  - MOTOKI MIYAZAWA
AU  - YUJI KITAHATA
AU  - MASAKI UENO
AU  - RYOHEI KOBAYASHI
AU  - ATSUSHI MIYAMOTO
AU  - YOSHITAKA WADA
AU  - SHINICHI ASAMURA
AU  - HIROKI YAMAUE
TI  - Pancreatectomy With Artery <em>En-bloc</em> Resection for Pancreatic Neck/Body Cancer: A Single-arm Pilot Study
AID  - 10.21873/anticanres.15476
DP  - 2022 Jan 01
TA  - Anticancer Research
PG  - 217--227
VI  - 42
IP  - 1
4099  - http://ar.iiarjournals.org/content/42/1/217.short
4100  - http://ar.iiarjournals.org/content/42/1/217.full
SO  - Anticancer Res2022 Jan 01; 42
AB  - Background/Aim: The potential benefits of pancreatectomy with major arterial resection have been studied in the past, but findings remain controversial. Pancreatic neck/body cancer (PNBC) involving arteries frequently requires combined resection of the pancreas, artery and portal vein. Patients and Methods: Nine prospectively-registered consecutive patients with PNBC were enrolled, all underwent pancreatoduodenectomy with common hepatic artery en-bloc resection (PD-CHAR). We investigated the safety of PD-CHAR by blood flow evaluation with intraoperative indocyanine green fluorescence imaging in reconstructed vessels/organs. Results: Among patients who underwent PD-CHAR, there was no severe morbidity. Artery/portal vein combined resection and reconstruction was performed in all patients. Four (44%) patients had pathological positivity for cancer cell invasion into the nerve plexus of artery at the site of radiographic artery involvement, although one (11%) was diagnosed with pathological artery involvement. Conclusion: PD-CHAR following neoadjuvant therapy might be feasible for PNBC without severe postoperative complications. Survival benefits in PNBC should be confirmed in further studies.