PT - JOURNAL ARTICLE AU - YUSUKE TAKASHIMA AU - SHUHEI KOMATSU AU - MASATAKA KASUGA AU - TAKUMA OHASHI AU - HIROTAKA KONISHI AU - ATSUSHI SHIOZAKI AU - TAKESHI KUBOTA AU - HITOSHI FUJIWARA AU - KAZUMA OKAMOTO AU - EIGO OTSUJI TI - Tumor Location on the Vertical Section of the Anterior Wall Is Related to Favorable Prognosis and Low Incidence of Lymph Node Metastasis in Lower-third Gastric Cancer AID - 10.21873/anticanres.15478 DP - 2022 Jan 01 TA - Anticancer Research PG - 237--243 VI - 42 IP - 1 4099 - http://ar.iiarjournals.org/content/42/1/237.short 4100 - http://ar.iiarjournals.org/content/42/1/237.full SO - Anticancer Res2022 Jan 01; 42 AB - Background/Aim: This retrospective study investigated the clinical significance of vertical location in gastric cancer (GC) and the optimal treatment strategy according to the vertical location. Patients and Methods: Between 1997 and 2018, 1,304 consecutive patients with GC who underwent curative surgical resection with lymphadenectomy were analyzed retrospectively. Results: Patients with GC in the anterior wall (AW) had a significantly better prognosis compared to those in other sites of the lower third stomach (p=0.040). Multivariate analysis showed that tumor location in the AW was an independent prognostic factor and was associated with a lower incidence of lymph node metastasis (LNM) (p=0.023). The frequency of LNM in the area of D2 was lower in patients with AW GC than those with GC in other locations. Conclusion: Patients with AW GC had a favorable prognosis, with a lower incidence of LNM in lower-third GC.