PT  - JOURNAL ARTICLE
AU  - KAWASUMI, KENJI
AU  - KAWANO, YOHEI
AU  - KUJIRAI, AZUSA
AU  - MANO, YASUNARI
AU  - MATSUI, REIKO
AU  - MAEDA-MINAMI, AYAKO
AU  - YAMAMOTO, YUICHIRO
AU  - NEGISHI, KENICHI
AU  - SHIMADA, SHUJI
AU  - YAMAGUCHI, MASAKAZU
AU  - NAGATA, MASASHI
AU  - AOYAMA, TAKAO
TI  - Risk Factors Associated With Unplanned Acute Care in Outpatient Chemotherapy With Oral Anticancer Drugs as Monotherapy or Combination Therapy With Injectable Anticancer Drugs
AID  - 10.21873/anticanres.15401
DP  - 2021 Nov 01
TA  - Anticancer Research
PG  - 5827--5834
VI  - 41
IP  - 11
4099  - http://ar.iiarjournals.org/content/41/11/5827.short
4100  - http://ar.iiarjournals.org/content/41/11/5827.full
SO  - Anticancer Res2021 Nov 01; 41
AB  - Background/Aim: Recently, the number of patients with cancer receiving outpatient chemotherapy using oral anticancer drugs has increased, but the currently available outpatient cancer chemotherapy is not safer than that available before. The present study aimed to identify risk factors associated with unplanned acute care (UAC) requiring outpatient chemotherapy-related consultation and hospitalisation. Patients and Methods: We conducted a case– control study among 1,674 patients who received oral anticancer drug treatment either alone or in combination with injectable anticancer drugs at National Cancer Center Hospital East, Japan, between December 1, 2014, and November 30, 2015. Results: Body mass index (BMI) was identified as a risk factor for UAC during chemotherapy. Patients with a BMI of <18.5 kg/m2, classified as underweight according to the World Health Organization classification of nutritional status, had a significantly higher risk of UAC. Conclusion: A low BMI immediately before the occurrence of chemotherapy-related UAC is a risk factor for adverse effects; therefore, underweight patients need more careful monitoring and supportive care.