RT Journal Article SR Electronic T1 Difficulties of Breast Reconstruction – Problems That No One Likes to Face JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 5365 OP 5375 DO 10.21873/anticanres.15349 VO 41 IS 11 A1 MICHAEL FRIEDRICH A1 STEFAN KRÄMER A1 DOMINIQUE FRIEDRICH A1 CLAYTON KRAFT A1 NICOLAI MAASS A1 CHRISTOPH ROGMANS YR 2021 UL http://ar.iiarjournals.org/content/41/11/5365.abstract AB Reconstructive breast surgery following total or partial mastectomy can be performed using autologous tissues or breast implants, and each has its own set of complications. Most women do not experience significant complications and are highly satisfied but breast reconstruction must consider potential complications from surgical techniques, as well as additional complications that may arise from oncological treatment modalities such as radiation therapy and chemotherapy. The aim of this article is to provide a systemic overview of possible complications that may arise in the course of reconstructive breast surgery. Complications associated with flap-based or implant-based breast reconstruction can be classified as: i) Complications inherent to surgery and common to all, including seroma, bleeding, and hematoma; skin necrosis; and infection, among others. ii) Complications specifically related to reconstruction, such as flap ischemia/necrosis/loss; fat necrosis; implant capsular contracture; implant failure, exposure, or malposition. In conclusion, this overview of possible complications is intended to improve the decision-making process when considering breast reconstruction.