RT Journal Article SR Electronic T1 Impact of Intraoperative Blood Loss and Blood Transfusion on the Prognosis of Colorectal Liver Metastasis Following Curative Resection JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 5617 OP 5623 DO 10.21873/anticanres.15377 VO 41 IS 11 A1 SHIBUTANI MASATSUNE A1 KENJIRO KIMURA A1 SHINICHIRO KASHIWAGI A1 WANG EN A1 YUKI OKAZAKI A1 KIYOSHI MAEDA A1 KOSEI HIRAKAWA A1 MASAICHI OHIRA YR 2021 UL http://ar.iiarjournals.org/content/41/11/5617.abstract AB Background/Aim: The identification of risk factors for recurrence after resection of colorectal liver metastasis is necessary in order to establish a more effective treatment strategy. In addition to well-known prognostic factors, such as the tumor diameter and number of metastatic tumors, a large amount of intraoperative blood loss (IBL) and blood transfusion have recently been reported to be associated with shorter long-term survival. The aim of this study was to assess the impact of IBL and blood transfusion on the prognosis of colorectal liver metastasis after curative resection. Patients and Methods: A total of 104 patients who underwent R0 resection for colorectal liver metastasis were enrolled in this study. Results: The high-IBL (>300 ml) group had significantly shorter relapse-free survival after hepatic resection in comparison to the low-IBL (≤300 ml) group (p=0.0025). Patients with blood transfusion had significantly shorter relapse-free survival after hepatic resection in comparison to patients without blood transfusion (p=0.0026). Conclusion: A large amount of IBL and blood transfusion may have a negative impact on long-term survival in patients who undergo hepatic resection for colorectal liver metastasis.