TY - JOUR T1 - Safety and Feasibility of Gastrectomy for Gastric Cancer in Patients Receiving Antiplatelet and/or Anticoagulation Treatment JF - Anticancer Research JO - Anticancer Res SP - 5605 LP - 5610 DO - 10.21873/anticanres.15375 VL - 41 IS - 11 AU - TORU AOYAMA AU - MASATO NAKAZONO AU - KENKI SEGAMI AU - SHINSUKE NAGASAWA AU - KENTARO HARA AU - HIROSHI TAMAGAWA AU - KEISUKE KOMORI AU - HIDEAKI SUEMATSU AU - YUKIO MAEZAWA AU - KAZUKI KANO AU - ITARU HASHIMOTO AU - TAKAONOBU YAMADA AU - TSUTOMU SATO AU - MASAKATSU NUMATA AU - NORIO YUKAWA AU - TAKASHI OGATA AU - YASUSHI RINO AU - TAKASHI OSHIMA Y1 - 2021/11/01 UR - http://ar.iiarjournals.org/content/41/11/5605.abstract N2 - Background/Aim: The number of patients who have cardiovascular-morbidities and use antiplatelet and/or anticoagulation therapy is rapidly growing worldwide. The present study evaluated the safety and feasibility of gastrectomy for gastric cancer in patients who received antiplatelet and/or anticoagulation therapy in the perioperative period. Patients and Methods: Cases were selected from the medical records of consecutive patients who were diagnosed with gastric cancer and underwent complete resection at the Kanagawa Cancer Center from 2013 to 2017. The patients were divided into the antiplatelet and/or anticoagulation treatment group and the non-antiplatelet and/or anticoagulation treatment group. Results: Five hundred and six patients underwent gastrectomy for gastric cancer and were analyzed in the present study. Among them, 62 patients (12.3%) received anticoagulation therapy (anticoagulation group). When the anticoagulation and non-anticoagulation groups were compared, although there were some differences in patient background factors, the surgical findings, perioperative clinical course, and details of postoperative complications were similar. The incidence of postoperative bleeding was 0.8% (4/506) in all patients. The incidence of postoperative bleeding was 1.6% (1/62) in the anticoagulation group and 0.7% (3/446) in the non-anticoagulation group. Preoperative anticoagulation therapy was not identified as a significant independent risk factor for postoperative bleeding. Conclusion: These results suggest that curative gastrectomy for gastric cancer is safe and feasible, regardless of the perioperative use of antiplatelet and/or anticoagulation treatment. In addition, the perioperative use of antiplatelet and/or anticoagulation treatment was not a significant risk factor for postoperative bleeding after gastrectomy for gastric cancer. ER -