RT Journal Article SR Electronic T1 Prognostic Factors of Potential Early Recurrence of Hypopharyngeal Carcinoma JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 5761 OP 5766 DO 10.21873/anticanres.15392 VO 41 IS 11 A1 BABA, DAISUKE A1 FUSHIMI, CHIHIRO A1 HANYU, KENJI A1 MASUBUCHI, TATSUO A1 TADA, YUICHIRO A1 MURA, KOKI YR 2021 UL http://ar.iiarjournals.org/content/41/11/5761.abstract AB Background/Aim: Prognostic factors of hypopharyngeal carcinoma have been reported previously. However, recurrent cases of this disease occurring within 6 months of treatment have been excluded or poorly documented in many studies. We aimed to evaluate the prognostic factors of hypopharyngeal carcinoma recurrence within 6 months. Patients and Methods: A total of 120 patients were eligible for this retrospective study. Recurrent cases of hypopharyngeal carcinoma occurring within 6 months of treatment were evaluated and compared with non-recurrent cases. Results: Recurrence within 6 months was detected in 28/50 cases. In univariate analyses, classification markers (pT≥4a and cN≥2b) were statistically significant prognostic factors for early recurrence (p=0.04 and p=0.04, respectively); however, only pT≥4a was predictive of recurrence in multivariate analyses (p=0.02). Conclusion: Risk stratification according to the prognostic factor pT≥4a will allow physicians to identify patients who should be followed meticulously within the first 6 months.