RT Journal Article
SR Electronic
T1 Prognostic Factors of Potential Early Recurrence of Hypopharyngeal Carcinoma
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 5761
OP 5766
DO 10.21873/anticanres.15392
VO 41
IS 11
A1 DAISUKE BABA
A1 CHIHIRO FUSHIMI
A1 KENJI HANYU
A1 TATSUO MASUBUCHI
A1 YUICHIRO TADA
A1 KOKI MURA
YR 2021
UL http://ar.iiarjournals.org/content/41/11/5761.abstract
AB Background/Aim: Prognostic factors of hypopharyngeal carcinoma have been reported previously. However, recurrent cases of this disease occurring within 6 months of treatment have been excluded or poorly documented in many studies. We aimed to evaluate the prognostic factors of hypopharyngeal carcinoma recurrence within 6 months. Patients and Methods: A total of 120 patients were eligible for this retrospective study. Recurrent cases of hypopharyngeal carcinoma occurring within 6 months of treatment were evaluated and compared with non-recurrent cases. Results: Recurrence within 6 months was detected in 28/50 cases. In univariate analyses, classification markers (pT≥4a and cN≥2b) were statistically significant prognostic factors for early recurrence (p=0.04 and p=0.04, respectively); however, only pT≥4a was predictive of recurrence in multivariate analyses (p=0.02). Conclusion: Risk stratification according to the prognostic factor pT≥4a will allow physicians to identify patients who should be followed meticulously within the first 6 months.