RT Journal Article
SR Electronic
T1 Topical Budesonide for Treating Giant Rectal Pseudopolyposis
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 2961
OP 2964
VO 25
IS 4
A1 PILICHOS, CHARALAMPOS
A1 PREZA, ATHENA
A1 DEMONAKOU, MARIA
A1 KAPATSORIS, DIMITRIOS
A1 BOURAS, CONSTANTINOS
YR 2005
UL http://ar.iiarjournals.org/content/25/4/2961.abstract
AB Pseudopolyps are a frequent finding in the course of inflammatory bowel disease. They are non-neoplastic lesions resulting from a regenerative and healing process that leaves inflamed colonic mucosa in polypoid configuration. Data about their management is lacking. “Giant” pseudopolyps can be mistaken for adenocarcinomas and, as they rarely regress with medical management alone, a surgical resection is often required. A case of giant pseudopolyposis treated non-surgically, in a patient with concomitant ulcerative colitis and chronic hepatitis B, is reported, representing a co-morbidity complicating an eventual conservative treatment. The clinical implementation of topical budesonide was originally tested, resulting in clinical, endoscopic and histological remission. Budesonide seems a promising therapy for IBD, particularly when a comorbidity with viral hepatitis exist. Copyright© 2005 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved