PT - JOURNAL ARTICLE AU - CHARALAMPOS PILICHOS AU - ATHENA PREZA AU - MARIA DEMONAKOU AU - DIMITRIOS KAPATSORIS AU - CONSTANTINOS BOURAS TI - Topical Budesonide for Treating Giant Rectal Pseudopolyposis DP - 2005 Jul 01 TA - Anticancer Research PG - 2961--2964 VI - 25 IP - 4 4099 - http://ar.iiarjournals.org/content/25/4/2961.short 4100 - http://ar.iiarjournals.org/content/25/4/2961.full SO - Anticancer Res2005 Jul 01; 25 AB - Pseudopolyps are a frequent finding in the course of inflammatory bowel disease. They are non-neoplastic lesions resulting from a regenerative and healing process that leaves inflamed colonic mucosa in polypoid configuration. Data about their management is lacking. “Giant” pseudopolyps can be mistaken for adenocarcinomas and, as they rarely regress with medical management alone, a surgical resection is often required. A case of giant pseudopolyposis treated non-surgically, in a patient with concomitant ulcerative colitis and chronic hepatitis B, is reported, representing a co-morbidity complicating an eventual conservative treatment. The clinical implementation of topical budesonide was originally tested, resulting in clinical, endoscopic and histological remission. Budesonide seems a promising therapy for IBD, particularly when a comorbidity with viral hepatitis exist. Copyright© 2005 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved