RT Journal Article SR Electronic T1 Treatments and Outcomes in Oligometastatic Soft Tissue Soft Sarcoma – A Single Centre Retrospective Analysis JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 5089 OP 5096 DO 10.21873/anticanres.15325 VO 41 IS 10 A1 GERARD M. WALLS A1 SHANE H. ZAIDI A1 NICOS FOTIADIS A1 SIMON JORDAN A1 MARCO MARUZZO A1 INTAN HAMID A1 OMAR AL-MUDERIS A1 KOMEL KHABRA A1 CHARLOTTE BENSON A1 ROBIN L. JONES A1 IAN R. JUDSON A1 AISHA B. MIAH YR 2021 UL http://ar.iiarjournals.org/content/41/10/5089.abstract AB Background/Aim: Distinguishing true oligometastatic disease from early polymetastatic disease is vital in patients with soft tissue sarcoma as contemporary treatment strategies differ significantly. Clinical factors such as tumour biology, organ involved, number of lesions, and patient fitness influence clinical decisions. Patients and Methods: A retrospective search of a prospective database identified patients with new distant relapse, treated between 2009 and 2012. Results: A total of 223 patients were included, and oligometastases were diagnosed in 81 (36%) patients, which were pulmonary in just over half of cases. These were treated with local therapy in 66 of 89 cases, and 7 patients received subsequent treatment for additional oligometastases. Metastasectomy was the most common treatment modality. A total of 16/66 patients (24%) underwent active surveillance for >6 months prior to local therapy. Conclusion: Patients with oligometastatic disease can experience durable disease control with timely multimodality treatment approaches for evolving metastatic disease, where disease biology allows.