RT Journal Article
SR Electronic
T1 Frequency and Risk Factors of Sleep Disturbances in Patients With Prostate Cancer Assigned to Local or Loco-regional Radiotherapy
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 5165
OP 5169
DO 10.21873/anticanres.15334
VO 41
IS 10
A1 KOPELKE, SVENJA
A1 BARTSCHT, TOBIAS
A1 SCHILD, STEVEN E.
A1 TVILSTED, SOEREN
A1 KJAER, TROELS W.
A1 RADES, DIRK
YR 2021
UL http://ar.iiarjournals.org/content/41/10/5165.abstract
AB Background/Aim: Many patients with prostate cancer receive definitive or adjuvant radiotherapy. This study aimed to identify the frequency of sleep disturbances and corresponding risk factors prior to radiation treatment. Patients and Methods: Data of 48 patients assigned to local or loco-regional irradiation for prostate cancer were retrospectively analyzed for pre-radiotherapy sleep disturbances. Fifteen characteristics were analyzed including age, performance status, comorbidity, history of previous malignancy, distress score, (emotional, physical or practical) problems, prostate-specific antigen, primary tumor stage, Gleason-score, upfront androgen deprivation therapy (ADT), treatment volume, brachytherapy, and COVID-19 pandemic. Results: Pre-radiotherapy sleep disturbances were reported by 20.8% of patients and significantly associated with distress scores ≥4 (p<0.0001) and ≥3 physical problems (p=0.0001). Trends were found for Karnofsky performance score ≤80 (p=0.095), Gleason score 7b-9 (p=0.079), and ADT (p=0.067). Conclusion: Pre-radiotherapy sleep disturbances were less common in prostate cancer patients than in other cancer patients. Risk factors were identified that can help identify patients requiring psychological support prior to radiotherapy.