TY - JOUR T1 - Postoperative Outcomes of Tangential <em>versus</em> Segmental Resection and End-to-end Reconstruction of the Superior Mesenterico-Portal Vein During Pancreatoduodenectomy for Pancreatic Adenocarcinoma: A Single-Center Experience JF - Anticancer Research JO - Anticancer Res SP - 5123 LP - 5130 DO - 10.21873/anticanres.15329 VL - 41 IS - 10 AU - HRYHORIY LAPSHYN AU - THERESA SCHULTE AU - NATALIE PETRUCH AU - EKATERINA PETROVA AU - KIM HONSELMANN AU - STEFFEN DEICHMANN AU - RÜDIGER BRAUN AU - BIRTE KULEMANN AU - JENS HOEPPNER AU - DIRK RADES AU - TOBIAS KECK AU - ULRICH F. WELLNER AU - DIRK BAUSCH AU - LOUISA BOLM Y1 - 2021/10/01 UR - http://ar.iiarjournals.org/content/41/10/5123.abstract N2 - Background/Aim: The impact of venous resections and reconstruction techniques on morbidity after surgery for pancreatic cancer (PDAC) remains controversial. Patients and Methods: A total of 143 patients receiving pancreatoduodenectomy (PD) for PDAC between 2013 and 2018 were identified from a prospective database. Morbidity and mortality after PD with tangential resection versus end-to-end reconstruction were assessed. Results: Fifty-two of 143 (36.4%) patients underwent PD with portal venous resection (PVR), which was associated with longer operation times [398 (standard error (SE) 12.01) vs. 306 (SE 13.09) min, p&lt;0.001]. PVR was associated with longer intensive-care-unit stay (6.3 vs. 3.8 days, p=0.054); morbidity (Clavien-Dindo classification (CDC) grade IIIa-V 45.8% vs. 35.8%, p=0.279) and 30-day mortality (4.1% vs. 4.2%, p&gt;0.99) were not different. Tangential venous resection was associated with similar CDC grade IIIa-IV (42.9% vs. 50.0%, p=0.781) and 30-day mortality rates (3.5% vs. 4.1%, p=0.538) as segmental resection and end-to-end venous reconstruction. Conclusion: Both tangential and segmental PVR appear feasible and can be safely performed to achieve negative resection margins. ER -