TY - JOUR T1 - Frailty Can Predict Prognosis After Hepatectomy in Patients With Colorectal Liver Metastasis JF - Anticancer Research JO - Anticancer Res SP - 4637 LP - 4644 DO - 10.21873/anticanres.15277 VL - 41 IS - 9 AU - KAZUNORI TOKUDA AU - YUJI MORINE AU - KATSUKI MIYAZAKI AU - SHINICHIRO YAMADA AU - YU SAITO AU - MASAAKI NISHI AU - TETSUYA IKEMOTO AU - MITSUO SHIMADA Y1 - 2021/09/01 UR - http://ar.iiarjournals.org/content/41/9/4637.abstract N2 - Background/Aim: The aim of this study was to investigate frailty as a prognostic factor in patients with colorectal liver metastasis undergoing hepatectomy. Patients and Methods: Eighty-seven patients who underwent hepatectomy at our institution were enrolled. Frailty was defined as a score of ≥4 on a clinical frailty scale. Patients were divided into frailty (n=29) and non-frailty (n=58) groups. Results: Overall and cancer-specific survival rates were significantly worse in the frailty group compared with the non-frailty group, and multivariate analysis revealed frailty as an independent prognostic factor. Disease-free survival tended to be worse in the frailty group. Fifty-eight patients relapsed after the first hepatectomy. Twenty-one of 58 recurrent patients were allocated to the frailty group. After recurrence, chemotherapy was significantly more frequently performed in the non-frailty group compared with the frailty group. Conclusion: Frailty can predict the prognosis of patients with colorectal liver metastasis undergoing hepatectomy. ER -