PT - JOURNAL ARTICLE AU - DIRK RADES AU - SVENJA KOPELKE AU - TAMER SOROR AU - STEVEN E. SCHILD AU - SOEREN TVILSTED AU - TROELS W. KJAER AU - TOBIAS BARTSCHT TI - Sleep Disorders Prior to Adjuvant Radiation Therapy for Gynecological Malignancies AID - 10.21873/anticanres.15246 DP - 2021 Sep 01 TA - Anticancer Research PG - 4407--4410 VI - 41 IP - 9 4099 - http://ar.iiarjournals.org/content/41/9/4407.short 4100 - http://ar.iiarjournals.org/content/41/9/4407.full SO - Anticancer Res2021 Sep 01; 41 AB - Background/Aim: Many patients with gynecological malignancies receive postoperative radiotherapy, which can lead to fear and sleep disorders. We aimed to identify the prevalence of and risk factors for sleep disorders. Patients and Methods: Sixty-two patients assigned to radiotherapy for gynecological malignancies were retrospectively evaluated. Seventeen characteristics were analyzed for associations with pre-radiotherapy sleep disorders including age, Karnofsky performance score, Charlson comorbidity index, history of additional malignancy, family history of gynecological cancer, distress score, emotional, physical or practical problems, tumor site/stage; chemotherapy, treatment volume, brachytherapy, and the COVID-19 pandemic. Results: The prevalence of pre-radiotherapy sleep disorders was 46.8%. Sleep disorders were significantly associated with Charlson comorbidity index ≥3 (p=0.012), greater number of physical problems (p<0.0001), and advanced primary tumor stage (p=0.005). A trend was found for greater number of emotional problems (p=0.075). Conclusion: Pre-radiotherapy sleep disorders are common in patients with gynecological malignancies, particularly in those with specific risk factors. Patients should be offered early psychological support.