PT - JOURNAL ARTICLE AU - MASAYA YAMANAKA AU - MASAMICHI HAYASHI AU - SUGURU YAMADA AU - FUMINORI SONOHARA AU - HIDEKI TAKAMI AU - YOSHIKUNI INOKAWA AU - DAI SHIMIZU AU - NORIFUMI HATTORI AU - MITSURO KANDA AU - CHIE TANAKA AU - GORO NAKAYAMA AU - MASAHIKO KOIKE AU - YASUHIRO KODERA TI - A Possible Definition of Oligometastasis in Pancreatic Cancer and Associated Survival Outcomes AID - 10.21873/anticanres.15189 DP - 2021 Aug 01 TA - Anticancer Research PG - 3933--3940 VI - 41 IP - 8 4099 - http://ar.iiarjournals.org/content/41/8/3933.short 4100 - http://ar.iiarjournals.org/content/41/8/3933.full SO - Anticancer Res2021 Aug 01; 41 AB - Background: Oligometastatic cancer (OM) is possibly associated with relatively better survival outcomes. We attempted to identify cases in line with this OM concept. Patients and Methods: A total of 130 cases with unresectable metastatic pancreatic cancer underwent non-curative surgery from April 2001 to December 2019. Sites of metastasis, clinicopathological information, and surgical outcomes were collected to formulate a better definition of OM. Results: OM criteria were defined as having metastasis to a single organ, few countable lesions and low serum cancer antigen 19-9 level. The median overall survival after non-curative surgery of OM cases was 13.0 months and was significantly better than that of non-OM cases (8.4 months, p=0.003). Conclusion: We propose single-organ metastasis of limited tumor volume (H1 or P1/2 by the Japanese Society of Cancer of the Colon and Rectum classification) and low serum cancer antigen 19-9 level (<2,000 U/ml) as new criteria for defining OM pancreatic cancer.