RT Journal Article SR Electronic T1 Effectiveness of Laparoscopic Combined Retroperitoneal and Transperitoneal Approach in Para-aortic Lymphadenectomy for Endometrial Cancer JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 4151 OP 4155 DO 10.21873/anticanres.15218 VO 41 IS 8 A1 MICHIKO KUBO-KANEDA A1 EIJI KONDO A1 RYO NIMURA A1 SHINTARO MAKI A1 MASAFUMI NII A1 KENTA YOSHIDA A1 TOMOAKI IKEDA YR 2021 UL http://ar.iiarjournals.org/content/41/8/4151.abstract AB Background/Aim: This study aimed to compare laparoscopy with laparotomy and evaluate the effectiveness of a laparoscopic combined retroperitoneal and transperitoneal approach for para-aortic lymphadenectomy in patients with endometrial cancer. Patients and Methods: In this single-center retrospective study, patients with endometrial cancer who underwent para-aortic lymphadenectomy between December 2016 and November 2019 were analyzed. The patient’s clinical and pathologic data were procured from medical records. Statistical analyses were performed using Fisher’s exact and the Mann–Whitney U-tests. Results: A total of 37 and 28 patients were included in the laparoscopic and laparotomy groups, respectively. The laparoscopic group had similar operative time, similar number of resected para-aortic and pelvic lymph nodes, less intraoperative blood loss and complications, lower rate of blood transfusion, and shorter postoperative stay than the laparotomy group. Conclusion: Laparoscopic combined retroperitoneal and transperitoneal approach for endometrial cancer is safe and effective compared to laparotomy.