PT - JOURNAL ARTICLE AU - MICHIKO KUBO-KANEDA AU - EIJI KONDO AU - RYO NIMURA AU - SHINTARO MAKI AU - MASAFUMI NII AU - KENTA YOSHIDA AU - TOMOAKI IKEDA TI - Effectiveness of Laparoscopic Combined Retroperitoneal and Transperitoneal Approach in Para-aortic Lymphadenectomy for Endometrial Cancer AID - 10.21873/anticanres.15218 DP - 2021 Aug 01 TA - Anticancer Research PG - 4151--4155 VI - 41 IP - 8 4099 - http://ar.iiarjournals.org/content/41/8/4151.short 4100 - http://ar.iiarjournals.org/content/41/8/4151.full SO - Anticancer Res2021 Aug 01; 41 AB - Background/Aim: This study aimed to compare laparoscopy with laparotomy and evaluate the effectiveness of a laparoscopic combined retroperitoneal and transperitoneal approach for para-aortic lymphadenectomy in patients with endometrial cancer. Patients and Methods: In this single-center retrospective study, patients with endometrial cancer who underwent para-aortic lymphadenectomy between December 2016 and November 2019 were analyzed. The patient’s clinical and pathologic data were procured from medical records. Statistical analyses were performed using Fisher’s exact and the Mann–Whitney U-tests. Results: A total of 37 and 28 patients were included in the laparoscopic and laparotomy groups, respectively. The laparoscopic group had similar operative time, similar number of resected para-aortic and pelvic lymph nodes, less intraoperative blood loss and complications, lower rate of blood transfusion, and shorter postoperative stay than the laparotomy group. Conclusion: Laparoscopic combined retroperitoneal and transperitoneal approach for endometrial cancer is safe and effective compared to laparotomy.