RT Journal Article
SR Electronic
T1 Indocyanine Green Fluorescence Image-guided Laparoscopic Hepatectomy Enabled Resection of a Tumor Invisible With Ultrasonography
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3867
OP 3869
DO 10.21873/anticanres.15180
VO 41
IS 8
A1 KEISUKE OURA
A1 TAKESHI AOKI
A1 YOSHIHIKO TASHIRO
A1 KAZUHIRO MATSUDA
A1 TOMOTAKE KOIZUMI
A1 TOMOKAZU KUSANO
A1 YUSUKE WADA
A1 HIDEKI SHIBATA
A1 TAKESHI YAMASHITA
A1 HIROMI DATE
A1 TOMOTAKE ARIYOSHI
A1 SATORU GOTO
A1 KIMIYASU YAMAZAKI
A1 MAKOTO WATANABE
A1 AKIRA FUJIMORI
A1 YUTA ENAMI
A1 KOJI OTSUKA
A1 ROBERT M. HOFFMAN
A1 MASAHIKO MURAKAMI
YR 2021
UL http://ar.iiarjournals.org/content/41/8/3867.abstract
AB Background: Ultrasonography (US) is widely used for pre-operative detection of liver tumors. However, US does not have high resolution and very small tumors, tumors located near the liver surface, or those in cirrhotic livers are often not detected. Case Report: A 47-year-old woman with a previous surgery for sigmoid colon cancer (T3N1bM0 Stage3b) showed a liver tumor on the surface of segment 2 by contrast-enhanced computed tomography (CT) and gadoliniumethoxybenzyldiethlenetriaminepen-taacetic acid (Gd-EOB-DTPA) magnetic resonance imaging (MRI). However, preoperative US could not identify a tumor lesion at the same site. The most likely preoperative diagnosis was metastasis from her sigmoid colon cancer and laparoscopic liver resection was performed. Intraoperative ultrasonography (IOUS) did not identify the tumor, but it was visualized with indocyanine green (ICG) fluorescence at the surface of segment 2. Laparoscopic liver resection was performed under fluorescence guidance. Pathological examination showed a pseudotumor with negative margins. Conclusion: ICG fluorescence imaging can allow visualization of liver tumors that are undetectable on US.