PT  - JOURNAL ARTICLE
AU  - KEISUKE OURA
AU  - TAKESHI AOKI
AU  - YOSHIHIKO TASHIRO
AU  - KAZUHIRO MATSUDA
AU  - TOMOTAKE KOIZUMI
AU  - TOMOKAZU KUSANO
AU  - YUSUKE WADA
AU  - HIDEKI SHIBATA
AU  - TAKESHI YAMASHITA
AU  - HIROMI DATE
AU  - TOMOTAKE ARIYOSHI
AU  - SATORU GOTO
AU  - KIMIYASU YAMAZAKI
AU  - MAKOTO WATANABE
AU  - AKIRA FUJIMORI
AU  - YUTA ENAMI
AU  - KOJI OTSUKA
AU  - ROBERT M. HOFFMAN
AU  - MASAHIKO MURAKAMI
TI  - Indocyanine Green Fluorescence Image-guided Laparoscopic Hepatectomy Enabled Resection of a Tumor Invisible With Ultrasonography
AID  - 10.21873/anticanres.15180
DP  - 2021 Aug 01
TA  - Anticancer Research
PG  - 3867--3869
VI  - 41
IP  - 8
4099  - http://ar.iiarjournals.org/content/41/8/3867.short
4100  - http://ar.iiarjournals.org/content/41/8/3867.full
SO  - Anticancer Res2021 Aug 01; 41
AB  - Background: Ultrasonography (US) is widely used for pre-operative detection of liver tumors. However, US does not have high resolution and very small tumors, tumors located near the liver surface, or those in cirrhotic livers are often not detected. Case Report: A 47-year-old woman with a previous surgery for sigmoid colon cancer (T3N1bM0 Stage3b) showed a liver tumor on the surface of segment 2 by contrast-enhanced computed tomography (CT) and gadoliniumethoxybenzyldiethlenetriaminepen-taacetic acid (Gd-EOB-DTPA) magnetic resonance imaging (MRI). However, preoperative US could not identify a tumor lesion at the same site. The most likely preoperative diagnosis was metastasis from her sigmoid colon cancer and laparoscopic liver resection was performed. Intraoperative ultrasonography (IOUS) did not identify the tumor, but it was visualized with indocyanine green (ICG) fluorescence at the surface of segment 2. Laparoscopic liver resection was performed under fluorescence guidance. Pathological examination showed a pseudotumor with negative margins. Conclusion: ICG fluorescence imaging can allow visualization of liver tumors that are undetectable on US.