%0 Journal Article %A HIDEMASA KUBO %A HISASHI IKOMA %A YUSUKE YAMAMOTO %A RYO MORIMURA %A JUN KIUCHI %A HIROKI SHIMIZU %A TOMOHIRO ARITA %A YOSHIAKI KURIU %A KAZUMA OKAMOTO %A EIGO OTSUJI %T Therapeutic Strategy of Colorectal Liver Metastasis Using Modified-JHBPS Nomogram %D 2021 %R 10.21873/anticanres.15156 %J Anticancer Research %P 3657-3665 %V 41 %N 7 %X Background/Aim: We attempted to stratify prognosis using the modified Journal of Hepato-Biliary-Pancreatic Sciences (mJHBPS) nomogram upon identification of colorectal liver metastasis (CRLM) and to investigate which strategy is better, surgery first (SF) or chemotherapy first (CF), in each risk group. Patients and Methods: A total of 137 patients with CRLM who underwent resection of the primary tumor were included. Patients with brain, bone, or perihilar lymph node metastases were excluded. Patients were scored using the mJHBPS nomogram upon identification of CRLM. Prognosis was investigated using event-free survival (EFS) and overall survival (OS). Results: The nomogram allowed stratification of patients using EFS and OS: low-risk (0-6 score, n=38), medium-risk (7-11 score, n=42), and high-risk (12≥ score, n=57). In the low-risk group, the EFS and OS of the CF group were significantly poorer than those of the SF group (p=0.019 and p=0.014, respectively). CF was an independent prognostic factor for both EFS and OS. Conclusion: The mJHBPS nomogram can stratify CRLM patients with sufficient differences in EFS and OS. SF was recommended for patients in the low-risk group. %U https://ar.iiarjournals.org/content/anticanres/41/7/3657.full.pdf