RT Journal Article
SR Electronic
T1 Comparison of Open and Thoracoscopic Esophagectomy in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma After Neoadjuvant Therapy
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3011
OP 3021
DO 10.21873/anticanres.15083
VO 41
IS 6
A1 HAMAI, YOICHI
A1 EMI, MANABU
A1 IBUKI, YUTA
A1 KUROKAWA, TOMOAKI
A1 YOSHIKAWA, TORU
A1 HIROHATA, RYOSUKE
A1 OHSAWA, MANATO
A1 KITASAKI, NAO
A1 OKADA, MORIHITO
YR 2021
UL http://ar.iiarjournals.org/content/41/6/3011.abstract
AB Background/Aim: The safety and effectiveness of thoracoscopic compared with open esophagectomy remain uncertain. We aimed to clarify the differences between these surgical modalities in patients with esophageal squamous cell carcinoma (ESCC) who underwent neoadjuvant therapy. Patients and Methods: We reviewed surgical outcomes among 133 patients with locally advanced ESCC who underwent neoadjuvant therapy followed by esophagectomy. We compared the operative outcomes, postoperative complications and survival rates between 65 and 68 patients who were respectively treated by open and thoracoscopic esophagectomy. Results: The surgical duration was longer, but blood loss was lower during thoracoscopic, compared with open esophagectomy. The numbers of dissected mediastinal lymph nodes and rates of postoperative complications did not significantly differ between open and thoracoscopic esophagectomy. However, the rates of postoperative pneumonia and recurrent laryngeal nerve paralysis were significantly lower and higher, respectively, after thoracoscopic, compared with open esophagectomy. Overall survival did not significantly differ between the groups. Conclusion: Thoracoscopic esophagectomy is feasible for patients with locally advanced ESCC who undergo neoadjuvant therapy.