RT Journal Article
SR Electronic
T1 Comparison of Risk Factors for Locally Advanced Lower Rectal Cancer Recurrence Evaluated by Magnetic Resonance Imaging and Pathological Factors Analysed by Longitudinal Slicing Method
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3169
OP 3178
DO 10.21873/anticanres.15103
VO 41
IS 6
A1 TAKUYA SHIRAISHI
A1 HIROOMI OGAWA
A1 SOMA KUMASAKA
A1 YUKI SHIMODA
A1 KATSUYA OSONE
A1 TAKUHISA OKADA
A1 YASUAKI ENOKIDA
A1 AKIHIKO SANO
A1 MAKOTO SAKAI
A1 TAKEHIKO YOKOBORI
A1 YOSHITO TSUSHIMA
A1 TETSUNARI OYAMA
A1 MAKOTO SOHDA
A1 KEN SHIRABE
A1 HIROSHI SAEKI
YR 2021
UL http://ar.iiarjournals.org/content/41/6/3169.abstract
AB Background/Aim: We compared the risk factors for locally advanced lower rectal cancer (LALRC) recurrence evaluated by preoperative magnetic resonance imaging (MRI) and pathological factors analysed via the longitudinal slicing method to identify high risk groups for recurrence. Patients and Methods: This retrospective single-institution cohort study analysed 45 consecutive patients who underwent curative surgery for LALRC. Data were analysed by an experienced radiologist and pathologist. Results: Final preoperative extramural venous invasion (EMVI) and extramural depth of invasion (EMD) determined via MRI were significantly associated with EMVI and EMD determined via pathological analysis. The log-rank test for disease-free survival based on initial preoperative factors showed significantly poor prognoses for circumferential resection margin (CRM)-positive, EMVI-positive, and EMD-positive patients. Conclusion: Final preoperative EMVI and EMD determined via MRI correlated with pathological EMVI and EMD, especially in patients who did not undergo preoperative treatment. CRM, EMVI, and EMD determined via preoperative MRI were significant risk factors for recurrence.