PT - JOURNAL ARTICLE AU - TAKUYA SHIRAISHI AU - HIROOMI OGAWA AU - SOMA KUMASAKA AU - YUKI SHIMODA AU - KATSUYA OSONE AU - TAKUHISA OKADA AU - YASUAKI ENOKIDA AU - AKIHIKO SANO AU - MAKOTO SAKAI AU - TAKEHIKO YOKOBORI AU - YOSHITO TSUSHIMA AU - TETSUNARI OYAMA AU - MAKOTO SOHDA AU - KEN SHIRABE AU - HIROSHI SAEKI TI - Comparison of Risk Factors for Locally Advanced Lower Rectal Cancer Recurrence Evaluated by Magnetic Resonance Imaging and Pathological Factors Analysed by Longitudinal Slicing Method AID - 10.21873/anticanres.15103 DP - 2021 Jun 01 TA - Anticancer Research PG - 3169--3178 VI - 41 IP - 6 4099 - http://ar.iiarjournals.org/content/41/6/3169.short 4100 - http://ar.iiarjournals.org/content/41/6/3169.full SO - Anticancer Res2021 Jun 01; 41 AB - Background/Aim: We compared the risk factors for locally advanced lower rectal cancer (LALRC) recurrence evaluated by preoperative magnetic resonance imaging (MRI) and pathological factors analysed via the longitudinal slicing method to identify high risk groups for recurrence. Patients and Methods: This retrospective single-institution cohort study analysed 45 consecutive patients who underwent curative surgery for LALRC. Data were analysed by an experienced radiologist and pathologist. Results: Final preoperative extramural venous invasion (EMVI) and extramural depth of invasion (EMD) determined via MRI were significantly associated with EMVI and EMD determined via pathological analysis. The log-rank test for disease-free survival based on initial preoperative factors showed significantly poor prognoses for circumferential resection margin (CRM)-positive, EMVI-positive, and EMD-positive patients. Conclusion: Final preoperative EMVI and EMD determined via MRI correlated with pathological EMVI and EMD, especially in patients who did not undergo preoperative treatment. CRM, EMVI, and EMD determined via preoperative MRI were significant risk factors for recurrence.