RT Journal Article
SR Electronic
T1 A New Survival Score for Patients Scheduled for Palliative Irradiation of Locally Advanced Carcinoma of the Head-and-Neck
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3055
OP 3058
DO 10.21873/anticanres.15088
VO 41
IS 6
A1 DIRK RADES
A1 CHRISTIAN STAACKMANN
A1 JULIKA RIBBAT-IDEL
A1 SVEN PERNER
A1 CHRISTIAN IDEL
A1 KARL L. BRUCHHAGE
A1 SAMER G. HAKIM
A1 STEVEN E. SCHILD
YR 2021
UL http://ar.iiarjournals.org/content/41/6/3055.abstract
AB Background/Aim: Patients with advanced squamous cell carcinoma of the head-and-neck (SCCHN) may be assigned to palliative irradiation. A survival score was developed for this group to support treatment personalization. Patients and Methods: Seventy-eight patients who received palliative irradiation for SCCHN and had complete data regarding performance score, pre-radiotherapy hemoglobin levels, and main tumor site were included in this retrospective study. Six-month survival rates of these factors were divided by 10 (factor scores) and added for each patient (total patient scores). Results: Total patient scores ranged between 8 and 15 points. Three groups were designed based on the 6-month survival rates, namely 8-9 (n=15), 11-13 (n=36), and 14-15 (n=27) points. Six-month survival rates were 13%, 28%, and 63%, and median survival times were 1, 2, and 11 months (p=0.001). Conclusion: A new survival score including three prognostic groups was developed. This new tool can help physicians when designing personalized treatments for patients with SCCHN scheduled for palliative irradiation.