RT Journal Article SR Electronic T1 Patient Quality of Life After Subpectoral Implant-based Breast Reconstruction With Synthetic or Biological Materials JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 3075 OP 3082 DO 10.21873/anticanres.15091 VO 41 IS 6 A1 RALF OHLINGER A1 ZAHER ALWAFAI A1 STEFAN PAEPKE A1 MAREK ZYGMUNT A1 FLORIAN NAWROTH A1 KATHARINA SCHÜLER A1 PATRICIA FRÖHLICH YR 2021 UL http://ar.iiarjournals.org/content/41/6/3075.abstract AB Aim: Quality of life and patient satisfaction after subpectoral breast reconstruction with meshes or acellular dermal matrices (ADM) and implants were assessed using the BreastQ questionnaire to investigate a potential influence of the materials on these parameters. Patients and Methods: The BreastQ questionnaire was completed by 121 patients, who had received material-assisted, heterologous, subpectoral breast reconstruction between 2010 and 2018. Results: Answers were similar independent of the reconstruction materials used. After prophylactic mastectomy, the physical wellbeing (chest) improved significantly with all materials (p=0.04). Postoperative radiotherapy significantly reduced satisfaction with outcome (p=0.005). Patients under 50 years old had significantly better postoperative sexual wellbeing than older patients (p=0.03). Conclusion: No influence was detected of the materials on the postoperative quality of life and patient satisfaction. An overall better quality of life was reported by younger and normal-weight patients with prophylactic or nipple-sparing mastectomy without radiotherapy.