PT - JOURNAL ARTICLE AU - RALF OHLINGER AU - ZAHER ALWAFAI AU - STEFAN PAEPKE AU - MAREK ZYGMUNT AU - FLORIAN NAWROTH AU - KATHARINA SCHÜLER AU - PATRICIA FRÖHLICH TI - Patient Quality of Life After Subpectoral Implant-based Breast Reconstruction With Synthetic or Biological Materials AID - 10.21873/anticanres.15091 DP - 2021 Jun 01 TA - Anticancer Research PG - 3075--3082 VI - 41 IP - 6 4099 - http://ar.iiarjournals.org/content/41/6/3075.short 4100 - http://ar.iiarjournals.org/content/41/6/3075.full SO - Anticancer Res2021 Jun 01; 41 AB - Aim: Quality of life and patient satisfaction after subpectoral breast reconstruction with meshes or acellular dermal matrices (ADM) and implants were assessed using the BreastQ questionnaire to investigate a potential influence of the materials on these parameters. Patients and Methods: The BreastQ questionnaire was completed by 121 patients, who had received material-assisted, heterologous, subpectoral breast reconstruction between 2010 and 2018. Results: Answers were similar independent of the reconstruction materials used. After prophylactic mastectomy, the physical wellbeing (chest) improved significantly with all materials (p=0.04). Postoperative radiotherapy significantly reduced satisfaction with outcome (p=0.005). Patients under 50 years old had significantly better postoperative sexual wellbeing than older patients (p=0.03). Conclusion: No influence was detected of the materials on the postoperative quality of life and patient satisfaction. An overall better quality of life was reported by younger and normal-weight patients with prophylactic or nipple-sparing mastectomy without radiotherapy.