RT Journal Article
SR Electronic
T1 Diagnostic Algorithm for Conjunctival Melanocytic Lesions
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3161
OP 3167
DO 10.21873/anticanres.15102
VO 41
IS 6
A1 MAGDALENA DĘBICKA-KUMELA
A1 BOZENA ROMANOWSKA-DIXON
A1 IZABELLA KARSKA-BASTA
A1 JOANNA KOWAL
A1 WERONIKA POCIEJ-MARCIAK
A1 ANNA MARKIEWICZ
YR 2021
UL http://ar.iiarjournals.org/content/41/6/3161.abstract
AB Background/Aim: This study aimed to develop an algorithm allowing the differentiation between conjunctival melanoma and other melanocytic infiltrations of the conjunctiva, on the basis of a dermatoscopic examination. Patients and Methods: A total of 160 conjunctival pigmented lesions were studied (40 melanomas and 120 non-melanoma conjunctival infiltrations). The clinical characteristics of the tumours were assessed with the use of dermatoscopic characteristics as described by Kittler, and with taking into consideration the typical characteristics of conjunctival lesions. Results: On the basis of modified dermatoscopic criteria, an algorithm was generated consisting of an assessment of the presence of 9 suspicious characteristics, e.g. more than two colours, colour asymmetry, pattern asymmetry, vascular polymorphism, presence of short vessels, linear vascular pattern, the presence of a peripheral structureless area, the presence of a grey structureless area and black dots in any part of the lesion. The presence of any of these characteristics scores 1 point. If a melanocytic lesion scores ≥3 points, the probability of diagnosing melanoma is on the level of p>0.001. Conclusion: The use of the proposed algorithm, based on modified dermatoscopic characteristics, may be a valuable tool for the diagnosis of conjunctival melanoma.