PT  - JOURNAL ARTICLE
AU  - TAKASHI UNO
AU  - AKI KANAZAWA
AU  - MIHO WATANABE NEMOTO
AU  - RINTARO HARADA
AU  - HIROKI KOBAYASHI
AU  - MAKOTO SAITO
AU  - YUMA IWAI
AU  - HIROKAZU USUI
AU  - AKIRA MITSUHASHI
AU  - MAKIO SHOZU
TI  - Radiation Therapy for Extrapelvic Lymph Node Recurrence After Curative Treatment for Cervical Cancer
AID  - 10.21873/anticanres.13190
DP  - 2019 Feb 01
TA  - Anticancer Research
PG  - 891--895
VI  - 39
IP  - 2
4099  - http://ar.iiarjournals.org/content/39/2/891.short
4100  - http://ar.iiarjournals.org/content/39/2/891.full
SO  - Anticancer Res2019 Feb 01; 39
AB  - Background/Aim: To investigate outcomes of patients with cervical cancer who received radiation therapy for extrapelvic lymph node recurrence after initial pelvic radiotherapy. Patients and Methods: The treatment charts of 20 patients were retrospectively reviewed, and factors influencing patient's prognosis were statistically analyzed. Results: The three-year in-field tumor control rate was 55% and overall survival (OS) at 2, 3, and 5 years was 55%, 45%, and 37.5%, respectively. The rate of the three-year OS in patients with recurrence within and after 9 months was 20% and 70%, respectively (p=0.016). None of the 4 patients who were diagnosed with supraclavicular lymph node recurrence alone at more than 9 months after initial treatment experienced further recurrence. Five-year survival of the remaining 16 patients was only 21% (p=0.021). Conclusion: Time to recurrence significantly influenced survival in patients with cervical cancer who received radiotherapy for extra-pelvic lymph node recurrence. Supraclavicular lymph node recurrence alone had a favorable impact on patient's prognosis.