<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">JAHNKE, A.</style></author><author><style face="normal" font="default" size="100%">MAKOVITZKY, J.</style></author><author><style face="normal" font="default" size="100%">BRIESE, V.</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Primary Melanoma of the Female Genital System: A Report of 10 Cases and Review of the Literature</style></title><secondary-title><style face="normal" font="default" size="100%">Anticancer Research</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2005</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2005-05-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">1567-1574</style></pages><volume><style face="normal" font="default" size="100%">25</style></volume><issue><style face="normal" font="default" size="100%">3A</style></issue><abstract><style  face="normal" font="default" size="100%">Background: Primary melanoma of the female genital system are extremely rare (2-3%). Patients and Methods: A retrospective review was undertaken of patients with primary melanoma of the female genital system treated from 1990-2003 at Rostock University Hospital, Germany. Different treatments (sentinel node biopsy, inguinofemoral lymphadenectomy, en bloc resection, adjuvant Interferon-alpha-therapy, adjuvant chemotherapy) are discussed. The complicated classification is reduced to a clinical path for daily use (UICC stage and invasion depth of Breslow, Clark's level and Chung's level). Results: We report on 10 patients, aged 26 to 76 years, with primary melanoma of the female genital tract. Seven women developed a vulvar melanoma and one woman a malignant melanoma of the cutaneous inguinal region, while another 2 women had an unusual primary location of the malignant melanoma, the cervico-vaginal region (n=1) and the left ovary (n=1). Conclusion: Initial surgical modality did not influence long-term survival, but affected disease-free survival significantly.</style></abstract></record></records></xml>