@article {JAHNKE1567, author = {A. JAHNKE and J. MAKOVITZKY and V. BRIESE}, title = {Primary Melanoma of the Female Genital System: A Report of 10 Cases and Review of the Literature}, volume = {25}, number = {3A}, pages = {1567--1574}, year = {2005}, publisher = {International Institute of Anticancer Research}, abstract = {Background: Primary melanoma of the female genital system are extremely rare (2-3\%). Patients and Methods: A retrospective review was undertaken of patients with primary melanoma of the female genital system treated from 1990-2003 at Rostock University Hospital, Germany. Different treatments (sentinel node biopsy, inguinofemoral lymphadenectomy, en bloc resection, adjuvant Interferon-alpha-therapy, adjuvant chemotherapy) are discussed. The complicated classification is reduced to a clinical path for daily use (UICC stage and invasion depth of Breslow, Clark{\textquoteright}s level and Chung{\textquoteright}s level). Results: We report on 10 patients, aged 26 to 76 years, with primary melanoma of the female genital tract. Seven women developed a vulvar melanoma and one woman a malignant melanoma of the cutaneous inguinal region, while another 2 women had an unusual primary location of the malignant melanoma, the cervico-vaginal region (n=1) and the left ovary (n=1). Conclusion: Initial surgical modality did not influence long-term survival, but affected disease-free survival significantly.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/25/3A/1567}, eprint = {https://ar.iiarjournals.org/content/25/3A/1567.full.pdf}, journal = {Anticancer Research} }