TY - JOUR T1 - Elevated Postoperative Levels of Serum C-reactive Protein Are Associated With Shorter Long-term Survival After Resection of Colorectal Liver Metastases, Regardless of the Occurrence of Infectious Complications JF - Anticancer Research JO - Anticancer Res SP - 2605 LP - 2610 DO - 10.21873/anticanres.15040 VL - 41 IS - 5 AU - MASATSUNE SHIBUTANI AU - KENJIRO KIMURA AU - SHINICHIRO KASHIWAGI AU - EN WANG AU - YUKI OKAZAKI AU - KIYOSHI MAEDA AU - KOSEI HIRAKAWA AU - MASAICHI OHIRA Y1 - 2021/05/01 UR - http://ar.iiarjournals.org/content/41/5/2605.abstract N2 - Background/Aim: Recently, elevated levels of postoperative inflammatory markers have been reported to be associated with poorer long-term survival outcomes, regardless of the occurrence of infectious complications, in gastroenterological malignancies. The aim of this study was to evaluate the association between postoperative inflammation and shorter long-term survival after resection of colorectal liver metastases. Patients and Methods: A total of 104 patients who underwent R0 resection for colorectal liver metastases were enrolled. The CRPmax levels were defined as the highest postoperative serum C-reactive protein levels during hospital stay. Results: The high-CRPmax group had a significantly lower relapse-free survival rate than the low-CRPmax group, regardless of the occurrence of infectious complications. Conclusion: In colorectal liver metastasis as well as other malignancies, elevated postoperative levels of serum C-reactive protein are associated with shorter long-term survival, regardless of the occurrence of infectious complications. ER -