RT Journal Article SR Electronic T1 Elevated Postoperative Levels of Serum C-reactive Protein Are Associated With Shorter Long-term Survival After Resection of Colorectal Liver Metastases, Regardless of the Occurrence of Infectious Complications JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 2605 OP 2610 DO 10.21873/anticanres.15040 VO 41 IS 5 A1 MASATSUNE SHIBUTANI A1 KENJIRO KIMURA A1 SHINICHIRO KASHIWAGI A1 EN WANG A1 YUKI OKAZAKI A1 KIYOSHI MAEDA A1 KOSEI HIRAKAWA A1 MASAICHI OHIRA YR 2021 UL http://ar.iiarjournals.org/content/41/5/2605.abstract AB Background/Aim: Recently, elevated levels of postoperative inflammatory markers have been reported to be associated with poorer long-term survival outcomes, regardless of the occurrence of infectious complications, in gastroenterological malignancies. The aim of this study was to evaluate the association between postoperative inflammation and shorter long-term survival after resection of colorectal liver metastases. Patients and Methods: A total of 104 patients who underwent R0 resection for colorectal liver metastases were enrolled. The CRPmax levels were defined as the highest postoperative serum C-reactive protein levels during hospital stay. Results: The high-CRPmax group had a significantly lower relapse-free survival rate than the low-CRPmax group, regardless of the occurrence of infectious complications. Conclusion: In colorectal liver metastasis as well as other malignancies, elevated postoperative levels of serum C-reactive protein are associated with shorter long-term survival, regardless of the occurrence of infectious complications.