TY - JOUR T1 - Treatment Volume, Dose Prescription and Delivery Techniques for Dose-intensification in Rectal Cancer: A National Survey JF - Anticancer Research JO - Anticancer Res SP - 1985 LP - 1995 DO - 10.21873/anticanres.14966 VL - 41 IS - 4 AU - LUCIANA CARAVATTA AU - MARCO LUPATTELLI AU - GIOVANNA MANTELLO AU - MARIA ANTONIETTA GAMBACORTA AU - GIUDITTA CHILOIRO AU - MONICA DI TOMMASO AU - CONSUELO ROSA AU - LUCREZIA GASPARINI AU - ALESSIO GIUSEPPE MORGANTI AU - VINCENZO PICARDI AU - RITA MARINA NIESPOLO AU - MATTIA FALCHETTO OSTI AU - SABRINA MONTRONE AU - NICOLA SIMONI AU - CATERINA BOSO AU - FRANCESCA FACCHIN AU - MARIA ASSUNTA DEIDDA AU - CRISTINA PIVA AU - CESARE GUIDA AU - LUIGI ZICCARELLI AU - FERNANDO MUNOZ AU - GIOVANNI BATTISTA IVALDI AU - VANIA MARCHETTI AU - PAOLA FRANZONE AU - CORRADO SPATOLA AU - PIERFRANCESCO FRANCO AU - VITTORIO DONATO AU - DOMENICO GENOVESI AU - on behalf of Gastrointestinal Study Group of AIRO (Italian Association of Radiation Oncology and Clinical Oncology) Y1 - 2021/04/01 UR - http://ar.iiarjournals.org/content/41/4/1985.abstract N2 - Background/Aim: The aim of the study was to investigate boost volume definition, doses, and delivery techniques for rectal cancer dose intensification. Patients and Methods: An online survey was made on 25 items (characteristics, simulation, imaging, volumes, doses, planning and treatment). Results: Thirty-eight radiation oncologists joined the study. Twenty-one delivered long-course radiotherapy with dose intensification. Boost volume was delineated on diagnostic magnetic resonance imaging (MRI) in 18 centres (85.7%), and computed tomography (CT) and/or positron emission tomography-CT in 9 (42.8%); 16 centres (76.2%) performed co-registration with CT-simulation. Boost dose was delivered on gross tumor volume in 10 centres (47.6%) and on clinical target volume in 11 (52.4%). The most common total dose was 54-55 Gy (71.4%), with moderate hypofractionation (85.7%). Intensity-modulated radiotherapy (IMRT) was used in all centres, with simultaneous integrated boost in 17 (80.8%) and image-guidance in 18 (85.7%). Conclusion: A high quality of treatment using dose escalation can be inferred by widespread multidisciplinary discussion, MRI-based treatment volume delineation, and radiation delivery relying on IMRT with accurate image-guided radiation therapy protocols. ER -