RT Journal Article
SR Electronic
T1 Treatment Volume, Dose Prescription and Delivery Techniques for Dose-intensification in Rectal Cancer: A National Survey
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 1985
OP 1995
DO 10.21873/anticanres.14966
VO 41
IS 4
A1 LUCIANA CARAVATTA
A1 MARCO LUPATTELLI
A1 GIOVANNA MANTELLO
A1 MARIA ANTONIETTA GAMBACORTA
A1 GIUDITTA CHILOIRO
A1 MONICA DI TOMMASO
A1 CONSUELO ROSA
A1 LUCREZIA GASPARINI
A1 ALESSIO GIUSEPPE MORGANTI
A1 VINCENZO PICARDI
A1 RITA MARINA NIESPOLO
A1 MATTIA FALCHETTO OSTI
A1 SABRINA MONTRONE
A1 NICOLA SIMONI
A1 CATERINA BOSO
A1 FRANCESCA FACCHIN
A1 MARIA ASSUNTA DEIDDA
A1 CRISTINA PIVA
A1 CESARE GUIDA
A1 LUIGI ZICCARELLI
A1 FERNANDO MUNOZ
A1 GIOVANNI BATTISTA IVALDI
A1 VANIA MARCHETTI
A1 PAOLA FRANZONE
A1 CORRADO SPATOLA
A1 PIERFRANCESCO FRANCO
A1 VITTORIO DONATO
A1 DOMENICO GENOVESI
A1 on behalf of Gastrointestinal Study Group of AIRO (Italian Association of Radiation Oncology and Clinical Oncology)
YR 2021
UL http://ar.iiarjournals.org/content/41/4/1985.abstract
AB Background/Aim: The aim of the study was to investigate boost volume definition, doses, and delivery techniques for rectal cancer dose intensification. Patients and Methods: An online survey was made on 25 items (characteristics, simulation, imaging, volumes, doses, planning and treatment). Results: Thirty-eight radiation oncologists joined the study. Twenty-one delivered long-course radiotherapy with dose intensification. Boost volume was delineated on diagnostic magnetic resonance imaging (MRI) in 18 centres (85.7%), and computed tomography (CT) and/or positron emission tomography-CT in 9 (42.8%); 16 centres (76.2%) performed co-registration with CT-simulation. Boost dose was delivered on gross tumor volume in 10 centres (47.6%) and on clinical target volume in 11 (52.4%). The most common total dose was 54-55 Gy (71.4%), with moderate hypofractionation (85.7%). Intensity-modulated radiotherapy (IMRT) was used in all centres, with simultaneous integrated boost in 17 (80.8%) and image-guidance in 18 (85.7%). Conclusion: A high quality of treatment using dose escalation can be inferred by widespread multidisciplinary discussion, MRI-based treatment volume delineation, and radiation delivery relying on IMRT with accurate image-guided radiation therapy protocols.