TY - JOUR T1 - Dosimetric Comparison of Radiation Therapy Using Hybrid-VMAT Technique for Stage I Esophageal Cancer JF - Anticancer Research JO - Anticancer Res SP - 1951 LP - 1958 DO - 10.21873/anticanres.14962 VL - 41 IS - 4 AU - YOSUKE TAKAKUSAGI AU - TERUFUMI KUSUNOKI AU - KIO KANO AU - WATARU ANNO AU - KEISUKE TSUCHIDA AU - NOBUTAKA MIZOGUCHI AU - ITSUKO SERIZAWA AU - HIROYUKI KATOH AU - TADASHI KAMADA AU - TAKATOMO EZURA AU - KATSUYUKI SHIRAI AU - DAISAKU YOSHIDA Y1 - 2021/04/01 UR - http://ar.iiarjournals.org/content/41/4/1951.abstract N2 - Background/Aim: This study focused on the hybrid-volumetric modulated arc therapy (hVMAT) for stage I esophageal cancer and compared the effects on dose distribution induced by changes in the ratio of three-dimensional conformal radiotherapy (3DCRT) to VMAT. Patients and Methods: Fifteen patients who underwent 3DCRT for cT1bN0M0 esophageal cancer at Kanagawa Cancer Center from January 2014 to April 2019 were included in the study. The dose–volume histogram (DVH) parameters of the target volume and normal organs were evaluated in the 3DCRT, hVMAT, and VMAT treatment plans. Results: The homogeneity index of the target volume was significantly lower for hVMAT. In hVMAT, as the ratio of VMAT increased, the volume of low-dose region in the heart and lung increased, whereas the volume of the middle- to high-dose region decreased. As the ratio of VMAT increased, the mean dose in the heart decreased, whereas the mean dose in the lung increased. Conclusion: Favorable dose concentration was obtained for the target volume in hVMAT for stage I esophageal cancer. Altering the ratio of VMAT significantly changed the DVH parameters in normal organs. ER -