RT Journal Article
SR Electronic
T1 Comparison of Inflammation-based Prognostic Scores in Patients With Biliary Tract Cancer After Surgical Resection
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 2147
OP 2155
DO 10.21873/anticanres.14987
VO 41
IS 4
A1 MASASHI UTSUMI
A1 KOJI KITADA
A1 NAOYUKI TOKUNAGA
A1 YUSUKE YOSHIDA
A1 TORU NARUSAKA
A1 RYOSUKE HAMANO
A1 HIDEAKI MIYASOU
A1 YOUSUKE TSUNEMITSU
A1 SHINYA OTSUKA
A1 MASARU INAGAKI
YR 2021
UL http://ar.iiarjournals.org/content/41/4/2147.abstract
AB Background/Aim: Inflammation-based prognostic scores are proven prognostic biomarkers in various cancers. This study aimed to identify a useful prognostic score for patients with biliary tract cancer (BTC) after surgical resection. Patients and Methods: This retrospective study recruited 115 patients with BTC during 2010-2020. The relationship between clinicopathological variables, including various prognostic scores and overall survival (OS), was investigated using univariate and multivariate analyses. Results: BTC included 58 cholangiocarcinoma, 29 gallbladder carcinoma, 16 ampullary carcinoma, and 12 perihilar cholangiocarcinoma cases. A significant difference was detected in OS of patients with a Japanese modified Glasgow prognostic score (JmGPS) 0 (n=62) and JmGPS 1 or 2 (high JmGPS) (n=53). In the multivariate analysis, tumour differentiation (p=0.014) and a high JmGPS (p=0.047) were independent prognostic factors. Conclusion: The high JmGPS was an independent prognostic predictor after surgical resection and was superior to other prognostic scores.