TY - JOUR T1 - Prognostic Reappraisal of Postoperative Carcinoembryonic Antigen in T1-2N0 Colorectal Cancer JF - Anticancer Research JO - Anticancer Res SP - 1101 LP - 1110 DO - 10.21873/anticanres.14868 VL - 41 IS - 2 AU - GUANGZHE PIAN AU - JUN SANG SHIN AU - SUNSEOK YOON AU - SEUNG YEOP OH Y1 - 2021/02/01 UR - http://ar.iiarjournals.org/content/41/2/1101.abstract N2 - Background/Aim: The purpose of this study was to compare the prognostic value of preoperative carcinoembryonic antigen (CEA), preoperative CEA/tumor size and postoperative CEA in stage I colorectal cancer. Patients and Methods: We analyzed a total of 305 consecutive stage I colorectal cancer patients who underwent a radical surgery at our Department. The patients were divided into low and high preoperative CEA groups, low and high preoperative CEA/tumor size groups, and low and high postoperative CEA groups according to the optimal cut-off values. Results: Multivariate analysis showed that postoperative CEA was independently associated with OS and DFS. However, the preoperative CEA and preoperative CEA/tumor size were not. Conclusion: The prognostic value of postoperative CEA is better than preoperative CEA and preoperative CEA/tumor size in patients with stage I colorectal cancer. Moreover, the common 5 ng/ml cut-off was not optimal for risk stratification in stage I colorectal cancer. ER -