TY - JOUR T1 - Intraoperative Shear Wave Elastography as a Quantitative Predictor of Pancreatic Fibrosis and Exocrine Function JF - Anticancer Research JO - Anticancer Res SP - 1013 LP - 1019 DO - 10.21873/anticanres.14856 VL - 41 IS - 2 AU - YUSUKE WADA AU - TAKESHI AOKI AU - AKIRA FUJIMORI AU - NOBUYUKI OHIKE AU - TOMOTAKE KOIZUMI AU - TOMOKAZU KUSANO AU - KAZUHIRO MATSUDA AU - KOJI NOGAKI AU - YOSHIHIKO TASHIRO AU - TOMOKI HAKOZAKI AU - HIDEKI SHIBATA AU - KODAI TOMIOKA AU - TAKAHITO HIRAI AU - KAZUHIKO SAITO AU - TATSUYA YAMAZAKI AU - MASAHIKO MURAKAMI Y1 - 2021/02/01 UR - http://ar.iiarjournals.org/content/41/2/1013.abstract N2 - Background/Aim: Soft pancreatic texture is a risk factor for postoperative pancreatic fistula (POPF). However, conventional evaluation of pancreatic texture is largely dependent on subjective assessment and lacks quantitative parameters. The study aimed to use ultrasonic shear wave elastography (SWE) to evaluate pancreatic stiffness to determine if the intraoperative SWE measurement could be a quantitative predictor for POPF. Patients and Methods: Fifteen patients scheduled for pancreaticoduodenectomy were included. Both pre- and intra-operative measurement of the pancreatic SWE index (SWEI) were evaluated. Relationships between intraoperative and preoperative SWEI, pathological fibrosis of the resected pancreatic specimen, postoperative exocrine function of the remnant pancreas, and the incidence of POPF were evaluated. Results: The intraoperative SWEI was correlated with the preoperative SWEI, pathological fibrosis of pancreatic tissue, and pancreatic exocrine function. Conclusion: Intraoperative SWE measurement of pancreatic elasticity may be useful as a quantitative method for evaluating pancreatic fibrosis and exocrine function. ER -