TY - JOUR T1 - Outcomes and Prognostic Factors Following Surgical Treatment of Pulmonary Metastases from Colorectal Carcinoma JF - Anticancer Research JO - Anticancer Res SP - 7045 LP - 7051 DO - 10.21873/anticanres.14731 VL - 40 IS - 12 AU - JOSEF VODIČKA AU - JAKUB FICHTL AU - JAKUB ŠEBEK AU - KRISTÝNA PROCHÁZKOVÁ AU - MARTIN SKÁLA AU - VLADISLAV TŘEŠKA AU - STANISLAV KORMUNDA AU - BOHUSLAVA VAŇKOVÁ AU - MARTIN SVATOŇ AU - ONDŘEJ TOPOLČAN AU - RADEK KUČERA Y1 - 2020/12/01 UR - http://ar.iiarjournals.org/content/40/12/7045.abstract N2 - Background/Aim: The lungs are the second most common site of cancer dissemination. The aim of this study was to analyze a cohort of patients operated for pulmonary metastases from colorectal carcinoma over a period of 18 years. Patients and Methods: In a group of 104 patients, relations were sought between overall survival or disease-free survival and preoperative levels of selected biomarkers, number of metastases and the condition of the intrathoracic lymphatic nodes. Median observation period was 63 months. Results: The 5-year survival rate was 54.3%. Risk of disease progression and risk of death increases in case of occurrence of 2 or more metastases, affection of intrathoracic lymph nodes and levels of CA 19-9, TPS or CEA above cut-off value. Conclusion: Prognostic factors that determine overall survival as well as disease-free survival are the number of metastases, the condition of intrathoracic lymphatic nodes and the preoperative levels of biomarkers. ER -