RT Journal Article SR Electronic T1 Differences Between Laparoscopic and Open Gastrectomy on the Impact of Postoperative Infectious Complications on Prognosis JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 7109 OP 7117 DO 10.21873/anticanres.14740 VO 40 IS 12 A1 HIROMI NAGATA A1 HIRONORI TSUJIMOTO A1 KEITA KOUZU A1 YUJIRO ITAZAKI A1 YUSUKE ISHIBASHI A1 SATOSHI TSUCHIYA A1 TAKAO SUGIHARA A1 NOZOMI ITO A1 MANABU HARADA A1 SHINSUKE NOMURA A1 YOJI KISHI A1 HIDEKI UENO YR 2020 UL http://ar.iiarjournals.org/content/40/12/7109.abstract AB Background/Aim: The aim of this study was to evaluate the impact of laparoscopic gastrectomy (LG) for gastric cancer on long-term survival in patients with postoperative infectious complications (PIC). Patients and Methods: A total of 608 patients who underwent gastrectomy were classified into two groups based on the surgical approach: LG (385 patients) and open gastrectomy (OG: 211 patients). Long-term survival after gastrectomy was compared between patients with and without PIC in both LG and OG groups. Results: Although the patients with PIC in OG group tended to have worse overall survival (OS) than those without PIC, the OS was not significantly different between the patients with and without PIC in LG group. Although multivariate analysis demonstrated that nodal involvement and PIC were significantly associated with OS in OG group, age and tumor depth, and not PIC, were associated with OS in LG group. Conclusion: PIC were negative predictors of clinical outcomes in patients with gastric cancer, particularly those who underwent OG, and long-term prognosis may be impacted less by PIC in patients undergoing LG.