RT Journal Article
SR Electronic
T1 Impact of BMI on Preoperative Axillary Ultrasound Assessment in Patients With Early Breast Cancer
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 7083
OP 7088
DO 10.21873/anticanres.14736
VO 40
IS 12
A1 INA MACAIONE
A1 ANTONIO GALVANO
A1 GIUSEPPA GRACEFFA
A1 SIMONA LUPO
A1 MARIO LATTERI
A1 ANTONIO RUSSO
A1 SALVATORE VIENI
A1 CALOGERO CIPOLLA
YR 2020
UL http://ar.iiarjournals.org/content/40/12/7083.abstract
AB Background: The accuracy of axillary ultrasound (AUS) with fine-needle aspiration with varying patient body mass index (BMI) is still unclear. The aim of our study was to evaluate whether the US features of axillary lymph nodes changes with BMI of patients. Patients and Methods: A retrospective review was performed involving 144 out of 270 patients with early breast cancer who underwent breast surgery with sentinel lymph node biopsy. Diagnostic efficacy of AUS in preoperative axillary nodal staging was assessed in relation to BMI. Results: Negative predictive values of AUS for the overweight and obese groups were statistically significantly lower compared to the normal/underweight group (p=0.02 and p=0.003, respectively). Additionally, Spearman’s correlation coefficient R between BMI and positive sentinel lymph node biopsy was 0.257, suggesting a significantly positive linear relationship between the two variables in the cohort overall. Conclusion: Our results demonstrate how in our cohort the negative predictive value of AUS was significantly influenced by adipose tissue and that the selection of the most suitable instrumental diagnostic technique might contribute to improving heterogeneous results.