TY - JOUR T1 - Impact of BMI on Preoperative Axillary Ultrasound Assessment in Patients With Early Breast Cancer JF - Anticancer Research JO - Anticancer Res SP - 7083 LP - 7088 DO - 10.21873/anticanres.14736 VL - 40 IS - 12 AU - INA MACAIONE AU - ANTONIO GALVANO AU - GIUSEPPA GRACEFFA AU - SIMONA LUPO AU - MARIO LATTERI AU - ANTONIO RUSSO AU - SALVATORE VIENI AU - CALOGERO CIPOLLA Y1 - 2020/12/01 UR - http://ar.iiarjournals.org/content/40/12/7083.abstract N2 - Background: The accuracy of axillary ultrasound (AUS) with fine-needle aspiration with varying patient body mass index (BMI) is still unclear. The aim of our study was to evaluate whether the US features of axillary lymph nodes changes with BMI of patients. Patients and Methods: A retrospective review was performed involving 144 out of 270 patients with early breast cancer who underwent breast surgery with sentinel lymph node biopsy. Diagnostic efficacy of AUS in preoperative axillary nodal staging was assessed in relation to BMI. Results: Negative predictive values of AUS for the overweight and obese groups were statistically significantly lower compared to the normal/underweight group (p=0.02 and p=0.003, respectively). Additionally, Spearman’s correlation coefficient R between BMI and positive sentinel lymph node biopsy was 0.257, suggesting a significantly positive linear relationship between the two variables in the cohort overall. Conclusion: Our results demonstrate how in our cohort the negative predictive value of AUS was significantly influenced by adipose tissue and that the selection of the most suitable instrumental diagnostic technique might contribute to improving heterogeneous results. ER -