TY - JOUR T1 - Synthesis and Antiproliferative Activity of [1,2,4]Triazino[4,3-<em>a</em>]indoles JF - Anticancer Research JO - Anticancer Res SP - 3775 LP - 3780 VL - 24 IS - 6 AU - PAOLA BARRAJA AU - PATRIZIA DIANA AU - ANTONINO LAURIA AU - ALESSANDRA MONTALBANO AU - ANNA MARIA ALMERICO AU - GAETANO DATTOLO AU - GIROLAMO CIRRINCIONE Y1 - 2004/11/01 UR - http://ar.iiarjournals.org/content/24/6/3775.abstract N2 - A series of [1,2,4]triazino[4,3-a]indoles was prepared in good yield by reacting 2-diazo-3-ethoxycarbonylindole with methylene active compounds. Derivatives of the title ring system were tested against a panel of 60 human tumor cell lines, and showed inhibitory activity against a wide range of cancer cell lines at micromolar concentration. Copyright© 2004 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved ER -