TY - JOUR T1 - Clinical Efficacy of Tumor Treating Fields for Newly Diagnosed Glioblastoma JF - Anticancer Research JO - Anticancer Res SP - 5801 LP - 5806 DO - 10.21873/anticanres.14597 VL - 40 IS - 10 AU - YANG LIU AU - MYLA S. STRAWDERMAN AU - KWANZA T. WARREN AU - MARGIE RICHARDSON AU - JENNIFER N. SERVENTI AU - NIMISH A. MOHILE AU - MICHAEL T. MILANO AU - KEVIN A. WALTER Y1 - 2020/10/01 UR - http://ar.iiarjournals.org/content/40/10/5801.abstract N2 - Background/Aim: Whether adding tumor treating fields (TTF) to the Stupp protocol increases survival for glioblastoma (GBM) patients in routine clinical care remains unknown. Patients and Methods: We retrospectively identified adult patients with newly diagnosed GBM (n=104) treated with the Stupp protocol or TTF at our Institution. Results: Thirty-six percent (37/104) of patients received TTF in conjunction with the Stupp protocol and these patients had increased 6-month (p=0.006) and 1-year (p=0.170), but not 2-year survival rates compared to the 67-patients who received Stupp alone. The improvement of survival rate at 6-month was further confirmed by a modified Poisson model (p=0.010). However, we did not observe any improvement in overall survival (OS) with a Cox model. Conclusion: While adding TTF to the Stupp protocol appeared to benefit patients with newly diagnosed GBM, this effect was mild and may be largely due to selection bias. ER -