@article {LIU5801, author = {YANG LIU and MYLA S. STRAWDERMAN and KWANZA T. WARREN and MARGIE RICHARDSON and JENNIFER N. SERVENTI and NIMISH A. MOHILE and MICHAEL T. MILANO and KEVIN A. WALTER}, title = {Clinical Efficacy of Tumor Treating Fields for Newly Diagnosed Glioblastoma}, volume = {40}, number = {10}, pages = {5801--5806}, year = {2020}, doi = {10.21873/anticanres.14597}, publisher = {International Institute of Anticancer Research}, abstract = {Background/Aim: Whether adding tumor treating fields (TTF) to the Stupp protocol increases survival for glioblastoma (GBM) patients in routine clinical care remains unknown. Patients and Methods: We retrospectively identified adult patients with newly diagnosed GBM (n=104) treated with the Stupp protocol or TTF at our Institution. Results: Thirty-six percent (37/104) of patients received TTF in conjunction with the Stupp protocol and these patients had increased 6-month (p=0.006) and 1-year (p=0.170), but not 2-year survival rates compared to the 67-patients who received Stupp alone. The improvement of survival rate at 6-month was further confirmed by a modified Poisson model (p=0.010). However, we did not observe any improvement in overall survival (OS) with a Cox model. Conclusion: While adding TTF to the Stupp protocol appeared to benefit patients with newly diagnosed GBM, this effect was mild and may be largely due to selection bias.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/40/10/5801}, eprint = {https://ar.iiarjournals.org/content/40/10/5801.full.pdf}, journal = {Anticancer Research} }