RT Journal Article SR Electronic T1 Controlling Nutritional Status (CONUT) Score Is a Prognostic Marker in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 4883 OP 4888 DO 10.21873/anticanres.12802 VO 38 IS 8 A1 NOBUYA DAITOKU A1 YUJI MIYAMOTO A1 RYUMA TOKUNAGA A1 YUKI SAKAMOTO A1 YUKIHARU HIYOSHI A1 MASAAKI IWATSUKI A1 YOSHIFUMI BABA A1 SHIRO IWAGAMI A1 NAOYA YOSHIDA A1 HIDEO BABA YR 2018 UL http://ar.iiarjournals.org/content/38/8/4883.abstract AB Background/Aim: The Controlling Nutritional Status (CONUT) score is a useful nutritional evaluation, that is calculated from serum albumin, total cholesterol concentrations, and total lymphocyte count. This study aimed to investigate the association between the CONUT score and prognosis in patients with metastatic colorectal cancer (mCRC). Patients and Methods: The CONUT score was retrospectively calculated in 211 patients with mCRC receiving first-line chemotherapy. The patients were divided into three groups: the CONUT low-group (0-1), intermediate-group (2-4), and high-group (5-). The associations of the CONUT score with clinicopathological factors and survival outcomes were evaluated. Results: The higher CONUT score was significantly associated with synchronous metastases, and no primary tumor resection. The higher CONUT score group showed a significant shorter progression-free survival (log-rank p<0.05) and overall survival (log-rank p<0.001). Conclusion: The CONUT score is a useful prognostic marker for predicting survival outcomes of patients with mCRC.