<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">WANG, LIMING</style></author><author><style face="normal" font="default" size="100%">HIRANO, YASUMITSU</style></author><author><style face="normal" font="default" size="100%">HENG, GREGORY</style></author><author><style face="normal" font="default" size="100%">ISHII, TOSHIMASA</style></author><author><style face="normal" font="default" size="100%">KONDO, HIROKA</style></author><author><style face="normal" font="default" size="100%">HARA, KIYOKA</style></author><author><style face="normal" font="default" size="100%">OBARA, NAO</style></author><author><style face="normal" font="default" size="100%">ASARI, MASAHIRO</style></author><author><style face="normal" font="default" size="100%">YAMAGUCHI, SHIGEKI</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Better Cancer-specific Survival in Younger Patients With Stage III Colorectal Cancer: A Propensity Score Matching Study From Japan</style></title><secondary-title><style face="normal" font="default" size="100%">Anticancer Research</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2020-08-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">4365-4372</style></pages><doi><style  face="normal" font="default" size="100%">10.21873/anticanres.14439</style></doi><volume><style face="normal" font="default" size="100%">40</style></volume><issue><style face="normal" font="default" size="100%">8</style></issue><abstract><style  face="normal" font="default" size="100%">Background/Aim: The purpose of this study was to explore the perioperative, short-term, and long-term prognostic differences in colorectal cancer (CRC) between young and older patients. Patients and Methods: A total of 3095 patients were divided into young (≤45 years; n=139) and older (&gt;45 years; n=2956) groups. Then, propensity score matching was performed for patients in stage I to III according to a ratio of 1:1. The clinicopathological factors and prognosis of the two groups were studied. Results: Young patients with CRC account for 4.49% of the total number of patients with CRC. Younger patients with CRC in stage I to III showed better cancer-specific survival (CSS). Older age was an independent risk factor for CSS prognosis. The CSS of the younger group was significantly better in stage I to III as a whole, but there was no difference in stage I and II subgroups – only in stage III. The proportion of young patients with stage III disease receiving first-line adjuvant chemotherapy was significantly higher. When young patients relapsed, they were more likely to receive second-line adjuvant chemotherapy or reoperation than older patients. Conclusion: Younger patients with stage III colorectal cancer had better CSS rates.</style></abstract></record></records></xml>