RT Journal Article
SR Electronic
T1 Predictors of Postoperative Ascites After Hepatic Resection in Patients With Hepatocellular Carcinoma
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 4343
OP 4349
DO 10.21873/anticanres.14437
VO 40
IS 8
A1 HARIMOTO, NORIFUMI
A1 ARAKI, KENICHIRO
A1 ISHII, NORIHIRO
A1 MURANUSHI, RYO
A1 HOSHINO, KOUKI
A1 HAGIWARA, KEI
A1 TSUKAGOSHI, MARIKO
A1 IGARASHI, TAKAMICHI
A1 WATANABE, AKIRA
A1 KUBO, NORIO
A1 SHIRABE, KEN
YR 2020
UL http://ar.iiarjournals.org/content/40/8/4343.abstract
AB Background: We retrospectively investigated factors predictive for ascites after hepatic resection to treat hepatocellular carcinoma (HCC). Patients and Methods: The data of 114 patients with HCC who underwent curative hepatic resection were reviewed. The patients were assigned to two groups according to the presence or not of postoperative ascites. Results: Ascites occurred in 16 patients (14.0%), and refractory ascites in four (3.5%). A MAC2-binding protein glycosylation isomer (M2BPGi) cutoff index of 1.61 [sensitivity=75.0%, specificity 67.9%, area under the curve (AUC)=0.745] and virtual touch tissue quantification (VTQ) of 2.62 (sensitivity=68.8%, specificity=89.8%, AUC=0.827) were the best cut-off values. Patients with ascites had lower serum albumin levels, higher serum creatinine levels, higher albumin-bilirubin (ALBI) grade, higher M2BPGi, higher VTQ, and longer operative time. ALBI grade 2 and both M2BPGi>1.61 and VTQ>2.62 were independent predictors of postoperative ascites. Conclusion: We demonstrated retrospectively that ALBI grade 2 and both high M2BPGi and VTQ were independent predictors of postoperative ascites in patients undergoing hepatic resection for HCC.